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Modern Physical Organic Chemistry ReviewPhys. Org. Chem. has always been one of my favorite subjects. As I continued to study chemistry during high school, college and grad school, I began to realise that phys org chem represents not so much a separate field as a philosophy and approach; to treat chemical and biological systems from the perspective of structure, conformation, and reactivity which are after all the most fundamental aspects of any such system. I realized that phys org chem is a truly interdisciplinary framework, and any one who has a solid background in it can be a good computational chemist, synthetic organic chemist, and/or bioorganic/biochemist.Unfortunately, all the classic phys org books until now have been of the 'pure' kind, focusing on mechanism and reactivity, but not discussing the interdisciplinary nature of the topic, especially for biological systems and materials. The wait is over: Modern Physical Organic Chemistry by Dennis Dougherty and Eric Anslyn has completely and satisfactorily reinvented the phys org chem textbook. Now one can look to a wholesome treatment of phys org as a multidisciplinary, fundamental, and exciting approach to both chemistry and biology. The book is worth its price, and covers the gamut of topics, including basic ones like mechanisms and bonding, but also is interspersed with lots of boxes and discussions explaining the applications of basic phys org concepts to host guest systems, proteins and nucleic acids, strained molecules, and materials science. Fantastic reference. It should make you a well-rounded chemist, which is a requirement in today's era of interdisciplinary and collaborative research.Modern Physical Organic Chemistry Overview
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