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Dendritic Spines ReviewThis new monograph on the dendritic spine belongs on the shelves of all neuroscients--after having been at the bedside for reading because one can't put it down. An obvious scholar as well as researcher, Yuste synthesizes a very large amount of data into an orderly series of chapters that describes the spine from the dendritic shaft to the most distal point of the filopodium. Starting with history and an homage to Cajal, Yuste starts by clearly articulating his biases. He then proceeds to discuss in nicely compartmentalized chapters everything from the structure of the spine to spines as calcium compartments to computational aspects of spine function. Although each chapter can be throught of as appealing to morphologists or physiologists or pharmacologists, the clear exposition and fluid writing make reading chapters "outside" of ones area of expertise a pleasure, and one rapidlly begins to assemble a sense of the spine. The only shortcoming is that even Yuste doesn't yet formally approach the issue of global behavior and spines---although comments scattered through the book (particularly in early and late chapters) leaves the reader with impressions of possible spine contributions. In an era of escalating prices that often places books out of the hands of readers, this volume, even with glosy color plates, is so modestly priced that one would have no hesitation in assigning it as a text for a class, leaving plenty of money left over to to discuss the spine at a local bar.Dendritic Spines OverviewWant to learn more information about Dendritic Spines?
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